I'm not using many, just three. The first is a must to keep the water level high enough to cover the heaters if the ATO breaks and I'm away for long enough for evap to b detrimental. Half the sump will be open.
I hesitate to ask, but how big/small is your sump and how long are you typically gone on trips for that to be a concern? Makes me think you have a sump with 2-3" of water running in it.

I have a 30 Long as a sump and it runs just under half-full. If the ATO were to fail, it would take several days - maybe even a week or two - for pumps to be exposed...and at least a few more days for the heaters to become exposed.
Setting that wall only makes that window of time all the much shorter before your return pump is toasted in that same scenario. Only instead of weeks it'll be able to happen in days since the return chamber will be tiny.
A 40B is 36" x 18".
An inch of water in that space is about
(36 x 18 x 1 = 648 cu in / 231 =) 2.8 gallons.
If you wall that off to only 10" x 18" (a typical return chamber space), you would only have to evaporate just over 3/4 of a gallon to drop the same 1". You have
only a quarter the amount of time to find the failure before something bad happens.
Even if you literally only wall half the sump off, that's still literally half the amount of "safety time" you have allotted to your situation. If you
really really want to have walls in your sump, it would make more sense to have a tiny heater/drain water chamber and to leave the majority of space to be controlled by the ATO sensor. Personally I don't even think that makes much sense though, given the bother and space-reduction in the rest of the sump.
Open-sump is definitely the way to go for safety and flexibility, IMO. I've had ATO's fail on as well as off in this model and never had an issues, BTW....but I'm not away for excessively long periods either.