If you are starting with 'normal' city water, IMHO it's unlikely that whatever is the contaminates would be harmful after going through and RO. And especially if you also us DI.
I'm curious, what is the TDS of the source water you use?
If you are on a well or have really bad city water (like Flint, MI situation with lead) I'd consider getting a couple of tests done. One for the source water to see all that was in it at the start and then what's in it after your RO/DI.
My city water runs a TDS of 350ppm and my RO/DI takes it to zero. But I have a fairly crazy RO/DI system. I would never have done this if I had to pay the price it sold for new. But a friend who had to give up his tank had bought it used and he gave me a steal of a deal. Before I had this system, my 'normal' RO/DI system would start at zero and when the RO only level got up to 20, I'd replace the membrane. The DI always took it down to zero. Before that, we were on a well and I gave up on DI as I had to change it far too often. And I regularly used RO water with a TDS of 10 to 20+ ppm. And I never had any water related issues with my tank.