problems I see here
aquabiomic's for sale items are being used in place of Jay's fish disease protocols, the fish losses are easy to correct on next round
Jay has an entire forum dedicated to disease controls, recommend= don't stock wet items from a pet store skipping fallow preps/it risks all your current fish after you do QT on them. in a tank that big/costly/anything added from a pet store goes through a separate fallow observation tank at your home, carefully ran.
alternate: stock no fish for a long time. build up your actual reef, fallow it in the end, then add qt prepped fish, any odds and ends thereafter get passed through your dual home system for fallow. this approach saves you from having to fallow separately hundreds of wet items that will eventually be stocked in a 200+ gallon setup.
no form of fallowing was applied to pet store stock additions: corals, cuc etc, that needs reversed
aquabiomic's for-sale testing cannot help any aspect of this tank or any other tank: it's a new form of testing we can use to see a tiny, tiny portion of the dna in the system and you can't use any aspect of it to ensure being disease-free. it has 0% applicable use for disease tracking or prevention: notice no aspect of aquabiomic's testing is used in Jay's disease forum, stickies, troubleshoots or recommends to any poster.
this new system should be sandbed free for about 2 years to ensure stability, then, if you want sand, add in fully rinsed/prepped sand. delay sandbed addition on the next round. if the tank wasn't so big you could just keep it clean early on but that's a monumental task in a 200+ gallon setup. sand management is a top headache unless you're very lucky and skilled at it, delayed use of sand is ideal considering your opening description.