Any media that you use will have to be tossed after the QT, so I typically take a little bit of matrix from my sump and add it to the HOB as extra insurance, along with a sponge (several of which I have in my sump in case I need to QT something). That small amount of media should not throw off copper levels too much, but you want to test to confirm. For water changes, depending on the bioload in the QT, I may change 25% (5 gallons) every 3-4 days. In my experience, the key to successful QT is plenty of flow (oxygen), and low bioload and water changes (ammonia).