Thank you, Randy, for your quick response. Does that evidence hold true in a sick tank too where a new cycle would be less stable than in a cycled reef tank? Your shared expertise is much appreciated.
What does a "sick" tank mean? The uptake mechanism for Nitrite in fish competes with the uptake method for Chloride. In saltwater, Chloride is an extremely common ion. (I think I saw an example of around 19000 ppm) In the study I found on the effects of Nitrites, they found that even 39 ppm Nitrites didn't have an effect on the fish in their study.
In a new tank, you may have more nitrite and it may stick around for longer, but the Chloride concentration in the water probably isn't much different than a mature tank so I wouldn't think there would be any difference. If the tank isn't cycled there is obviously a possibility of higher levels of Ammonia. The Nitrate level as well as leaching of various chemicals from live rock can occur during cycling which could also affect fish.


