I don't think there's a perfect answer. I personally never chose a UV because I didn't want to kill bacteria in the water. I wanted them to either stay in the water as food, or be skimmed out whole. Killing them will cause then to die and spill their guts before being skimme dout. That seems undesirable to me, but I can't prove it is a problem. Over time you may select for more benthic (growing on the bottom) and less planktonic (suspended in the water) bacteria. I do not know if that is good or bad.
In general, I think if you feel a UV is desirable for your system due to disease issues, then I'd go for it. I'm just not sure how needed/useful that effect is.