I run one periodically if needed.. good for quickly clearing up water born algae or bacterial outbreaks.
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Purchased one after my last velvet outbreak that took 3/4 my fish. Like mentioned before, get a good one. Run the flow slow if your concerned with pathogens. Works great for me. Yes ultra clear water and not a sign of ich or velvet for more than a year and I have added new fish. I dose Vinegar and no issue keeping my nutrients low so it’s not killing all the good bacteria.

