I've only had the pox a couple of times, but haven't lost much when I had them. It seems like when I've had issues, the temperature in the tank got high a little higher than normal for a few days, they zoas were right on top of each other, or, I hadn't done a water change in a while. This apparently hasn't worked for others, but I've been able to get mine under control with reducing the water temp and increasing water changes for a while. I've never tried dips for pox.