I agree that we could do much better with nutrition, stress management through water quality and adjunct therapies such as UV sterilizers and such. But you cannot strip a fish's immune system through quarantine. WBCs such as lymphocytes have great memory. And there is the complement innate system to the immune system as well. That doesnt disappear immediately just because you do tank transfer or copper. Conditioning a fish may make it more hearty and hopefully survive the parasite, but if they havent been exposed they still wont have the antibodoes to fight it off should velvet and sometimes ich in a system. Same for animals I work with, I'd rather vaccinate and avoid rather than make sure they are in great condition and hope they can survive diseases like parvo and such. So to each his own. Thanks for the dialog! It's always goo to see both sides so we can move forward as a hobby. I do absolutely agree with you that doing things to better condition our fish and improve their quality of life will improved overall survival and hopefully help fight off diseases if they occur. But I'm still not gonna chance my entire tank even for holy grail fish. I'll wait for them to be quarantined (by someone else respected by all) then consider placing them into my tank.