When you leave you aren’t breathing co2 into the house and the ph will increase which can also cause alk and ca to drop if there’s increased growth. Get a cheap co2 monitor and then look into co2 scrubbing, outside air line for skimmer, erv/hrv, leaving a window open when away, etc. just food for thought but might not be the answer
Edit. The changes can be drastic if you’re a family of four with a couple dogs that you board or take with you on vacation. Does anyone in the house get headaches when at home? Also if your dosing anything that increases ph to compensate for low ph when you’re home it will magnify when away if you have high co2 in the house normally and low co2 when you leave