Flame angel died, need help on next step

I noticed you treated with praziquantel. You could have had a resistant fluke, but because you treated prophylactically, I would think a combination of low oxygen levels and high nitrates caused undue stress to the fish, weakening it's immune system. In my experience, flame angels don't do well in high nitrates. You said the fish never ate well in quarantine during treatment. It does not look emaciated in the picture, but it doesn't take long for a fish become weak from insufficient food intake. Unfortunately, the API copper test kit is unreliable, so you may never know the cause of death.

I am sorry for your loss.

The high nitrates were not in the QT, where the fish was eating well. The high nitrates were in the DT, but the nitrates were at or near zero and then I increased my feeding and even added a small amount of potassium nitrate. Then they spiked in the last few days to about 80 ppm....which may have contributed to my problem. I think sashaka is right....you have to research and make your own decisions and live/learn from them. This is the second flame that I have lost. The first was due to ammonia poisoning during TTM. I wanted to avoid the copper with the angel and made a costly mistake trying to do it. I plan on buying a third angel but this time will be different. If I go copper, it will be w copper power (not coppersafe) for 30 days, lots of O2, I will use a hanna tester and NOT the API kit. And ramp up mores slowly. I am learning that patience is the key to success.

If it is TTM, I will decrease the tank transfer intervals from 72 hrs to 48 hrs but still do it over a 12 day period. This should help w the ammonia spike.

I am not confident in the LFS or on line purchases. Though I believe my only two losses (angels) are due to my inexperience, I must treat somehow...copper or TTM. I wish I could get my hands on some quality CP, but so far, no luck.

I do appreciate everybody jumping in to try and help me. Lots of great info with different opionions...but that is a good thing because it opens one's eyes.
 
It's of topic from the the OP but for what it matters I'm with @Lasse on this one.
When ever I get a new fish (it's rare for me as fish live long in my tank) but first thing I do acclimate 10 to 15 min, from there on in a FWB and then in the QT just to observe and see what the fish all eat.
Fish will stay QT 8 to 12 weeks to build up strength and feel comfortable to be in captivity.
If I see problems I treat accordingly but not of the back.
Ich will be always a TTM but have meds on hand just in case.
Just dropped close to $100 of meds in the trash to replace for new batch.
Many meds expire and treating with expire meds won't do much or nothing to a sick fish.
But it been a long time I used meds on a fish.
Being 22 years in the "Republic of Texas" ;) things in Europe have changed over the years.
That time not much hobbyist did quarantine fish or corals but with with the mass import of fish now days it's just almost undeniable to not having having a QT.
Even is it just to observe at first.
 
@Lasse With all due respect, the "fish disease situation" in Europe is very different than what's currently going on here in the US. (I've maintained saltwater aquariums in both places.) Back when I lived in London, passive observation in QT was usually all that was necessary. And when we moved back to the US, Cryptocaryon seemed to be more of a problem than Amyloodinium. Nowadays the latter has become an epidemic over here and most of the fish I lose in QT have velvet trophonts when I scrape the gills. Therefore, prophylaxis using Chloroquine or Copper has become a necessary evil in most cases.
 
They are, however, quite sensitive to ammonia

4FordFamily mentions a good point. Some tips that have worked for me...

1) Get an ammonia badge for the sick tank. Chemical test kits don't work with copper. See link below: https://www.chewy.com/seachem-alert...MI2Prd9uDJ2wIVXrXACh19Ygq7EAQYASABEgLl0PD_BwE

2) I also always have Marinepure blocks and chunks fully cycled waiting in one of my sumps to start up a sick tank. The sick tank instantly cycles with this stuff. It's awesome! I use a large enough piece that it even handles antibiotics - usually without affecting the bio load, though I still monitor closely just in case. :) https://www.bulkreefsupply.com/mari...MIspbRpuHJ2wIVEb7ACh2kTgbwEAQYBSABEgK3h_D_BwE

Others here may have additional tips that will help your next go at using copper more successful.
Good luck with your next flame! I know I'll always have one in one of my tanks. To me, they are one of the most beautiful dwarf angels one can own. :) You can see my flame in my avatar pic beneath my dentro coral.
 
Last edited:
If kept in copper 14 days then transferred to a sterile tank then due to the life cycle of ich and velvet you’ve effectively rid the fish of it, if administered properly.

You can use that method for at least white spot without any copper treatment at all.

During the last 10 years, I have helped a friend that import fishes from different Indonesia companies, One Philippine company and one Sri Lanka company. I did a fast calculation that it must been around 20 000 fishes passing through our hands. The only treatment method he uses is a very strong UV filtration system of professional grade.

IMO – the fishes from these companies according to quality and health of the them has been improved during the last 10 years. I know that these companies deliver to US too. Very seldom a DOA over 2-3 % and very seldom any health or parasite problems. I do not think I have seen velvet even once and white spot – if it will be - it is normally limited to Power Blue or “Doris”. Some species is more difficult to have to eat or show more stress related health problem compared with others, but illness caused by microorganisms has been very rare during these years.

Therefore – I do not believe that the health problem you guys seem to have come from the exporting countries. I do not know anything about the whole sale companies in the US – or LFS – but in Europe there is also whole sellers that´s not my first choice – but also those that I do not hesitate a minute to take fish directly from and put in my aquaria without QT.


@Diesel – I do not know the situation in whole Europe – only in my own country – but one of the wholesalers that I do not want to buy my fish from is situated in your home country as I know.

Most of diseases among fishes are stress related and I understand that even inside US – there is long transports – often > 24 hour in the bag. With this type of transports ammonia levels building up in the transport bag is of major concern. The normal acclimation protocol – drip or gradual acclimation – can be a stressful/deadly tool in those cases (being in the bag for > 24 hour). The best method in this case (fish in plastic bag > 24 hours) is something like this.

Prepare a receiving tank with water from your QT or your aquarium. Use CO2 and lower the pH to just under 7.

Open the box – let light come into the fishes for ½ hour. Work in low light but as must be able to observe the fishes.

If there is temperature difference – after ½ hour - transfer the bags to the new tank and let it temperate for a while.

If the fishes showing signs of lethargy in one or more bags – repack these bags. Open up – press out the old gas – fill up with new oxygen if you have – otherwise with fresh oxygen rich air – but do not bubble it into the bag – just repack in a normal way. Let the repacked bags be for around 1 hour.

After temperature acclimation (if needed) transfer the fishes directly to the low pH receiving aquaria without any water from the bags.

After that all fishes is transferred to the low pH receiving aquaria – start aeration of the low pH aquaria. This will slowly rise the pH and the next day you can transfer your fish to your QT or to your aquaria.

During the whole process – work slow – do not stress the fish – do not feed before you have transferred your fish into QT or DT.


Another method is to use an ammonia blocking agent in the bag – but as I understand – you can´t use that if there is copper in the transport water or in your receiving tank.

I always transfer my fish to my refugium (very much of pods there) and let them stay there for a week or two before transfer to my DT. Observe – I do it with fish that I know its healthy and in a country that are rather free of different illness. I do not say that QT is wrong – at least if you do not use prophylactic methods.

What I´ll try to say is that maybe the method to use prophylactic´s has been so widely used in the US that resistant population of some microorganisms has evolved. There is also other problems with using drugs to treat fishes (with drugs I also count in cupper). To be effective – drugs must be toxic in one or another way and it is only the dosage that judge if it will kill or treat our fishes. If it is a toxic substance – it must be (even if it is in low concentrations) made harmless (detoxification) by the fish and be transported out from the body or be bound in the fat of the fish (read chlorine organics).

The detoxification process happens mostly in the liver in an enzyme system (enzyme cascade) called the MFO system and especially the P-450 enzyme system. In a cascade of processes – the toxic substance gradually will be change to the end product - a more tolerated substance or an ineffective. But this system is a cascade of enzymatic processes – every enzyme creating metabolites that will be processed in the next step. This temporary metabolite can be more toxic than the original substance – therefore is important that the process can work without any breaks. A famous compound - just stopping this process in a certain step with a toxic substance – is antabuse (disulfiram). It stops the breakdown of alcohol in a certain step – leaving a metabolite that you do not feel very well with. And there are people that does not have a good enzymatic breakdown process for alcohol in their MFO – these get drunk fast and for a long period.

And – more to come – the MFO system is an evolutionary system – the enzymes in the P-450 system can be changed to co-enzymes in order to take care of substances it has never seen before. These substances are named inducer and there is a lot of them. The problem with them is that the co-enzyme produced of them can be fatal for the normal treatment of endogenous substances – they can attack wrong part of the molecule – hence create dangerous metabolites of endogenous substances. A lot of chlorine organics is well known to act in this way.

Among drugs acting on the P-450 enzyme system (in one or another way) are (no surprise for me) Chloroquine, metronidazole, erythromycin and fluconazole – all in normal us in the US but forbidden for use without a description of a veterinary in Sweden. I also think that all of these can create resistant population of different microorganisms – however not sure on all four.

With the chlorine organics – there is another troubling fact. These substances are soluble in fat – Fat is the primary energy source for fishes and store fat as reserves. This means that they also store things that are solved in fat. Total chlorine content in fishes can be high. What do you use the energy reserves to? Exact – when you have use for energy and do not get it through your food. Transport, stress and other factors will use energy – energy comes from the fat – fat disappear, and the solved chlorine organics comes out in the blood system again. There is some evidences that a M-74 (a known illness among Baltic salmons) is caused by this release of organic chlorines in the bloodstream. High levels of antioxidants seems to counteract this.

About the use of copper at low concentrations – there is a lot of literature – Just Google “sublethal exposure of copper fish

This post become long and complicated - therefore some words about another circumstance that make the use of pre-treatment for salt water species a little bit more complicated :) . A saltwater fish drinks a lot but pee very little – if all. The normal transfer path for substances that has been processed by the detoxification system (they have become more soluble in water) are through the kidneys and the pee. The salt water species do not pee as much as freshwater species – this means that the residues of different compounds will be in the fish body much longer and the rate of detoxification can be altered.

I will not more than mention the problems with introducing a already weakened fish to a new bacterial and parasite environment. The sickness can be induced from your home aquaria too!

Back to the original question

Facts show –

At the collector station/export facilities there can be use of both copper, chloroquine and other drugs.

At the wholesaler – the same situation

At the LFS – the same situation

At home - ?


This means that the poor fish in 30 to 60 days can been treated with low level of copper the whole time and been out for 3 treatments of the same drug (and you do not know the concentrations) – this before it arrives to your home – and you are starting a new cycle of treatment without any signs of diseases?

If there are signs of disease – treat – no doubt – but do not fix anything that´s not broken.

Somewhere this spiral must end - best has been if it end already at the wholesalers.

Sincerely Lasse
 
For me it is a FW bath, then a prazi bath, then into Qt for observation. In the last 5 years I never needed to do anything else. Without the FW bath I have lost fish with using only Prazi. One of my LFS said when he kept his incoming Flame Angels out of his copper systems he stopped losing them. For me I just stay away from Xmas Island Flame Angels, I like Vanuatu collected.
 
For me it is a FW bath, then a prazi bath, then into Qt for observation. In the last 5 years I never needed to do anything else. Without the FW bath I have lost fish with using only Prazi. One of my LFS said when he kept his incoming Flame Angels out of his copper systems he stopped losing them. For me I just stay away from Xmas Island Flame Angels, I like Vanuatu collected.

FYI https://www.researchgate.net/publication/299655993_Praziquantel_degradation_in_marine_aquarium_water


Sincerely Lasse
 
I'm new to the hobby, but I didn't start having success until I stopped drug prophylaxis, save for a 30 minute dip in 75 ppm hydrogen peroxide.
 
You can use that method for at least white spot without any copper treatment at all.

During the last 10 years, I have helped a friend that import fishes from different Indonesia companies, One Philippine company and one Sri Lanka company. I did a fast calculation that it must been around 20 000 fishes passing through our hands. The only treatment method he uses is a very strong UV filtration system of professional grade.

IMO – the fishes from these companies according to quality and health of the them has been improved during the last 10 years. I know that these companies deliver to US too. Very seldom a DOA over 2-3 % and very seldom any health or parasite problems. I do not think I have seen velvet even once and white spot – if it will be - it is normally limited to Power Blue or “Doris”. Some species is more difficult to have to eat or show more stress related health problem compared with others, but illness caused by microorganisms has been very rare during these years.

Therefore – I do not believe that the health problem you guys seem to have come from the exporting countries. I do not know anything about the whole sale companies in the US – or LFS – but in Europe there is also whole sellers that´s not my first choice – but also those that I do not hesitate a minute to take fish directly from and put in my aquaria without QT.


@Diesel – I do not know the situation in whole Europe – only in my own country – but one of the wholesalers that I do not want to buy my fish from is situated in your home country as I know.

Most of diseases among fishes are stress related and I understand that even inside US – there is long transports – often > 24 hour in the bag. With this type of transports ammonia levels building up in the transport bag is of major concern. The normal acclimation protocol – drip or gradual acclimation – can be a stressful/deadly tool in those cases (being in the bag for > 24 hour). The best method in this case (fish in plastic bag > 24 hours) is something like this.

Prepare a receiving tank with water from your QT or your aquarium. Use CO2 and lower the pH to just under 7.

Open the box – let light come into the fishes for ½ hour. Work in low light but as must be able to observe the fishes.

If there is temperature difference – after ½ hour - transfer the bags to the new tank and let it temperate for a while.

If the fishes showing signs of lethargy in one or more bags – repack these bags. Open up – press out the old gas – fill up with new oxygen if you have – otherwise with fresh oxygen rich air – but do not bubble it into the bag – just repack in a normal way. Let the repacked bags be for around 1 hour.

After temperature acclimation (if needed) transfer the fishes directly to the low pH receiving aquaria without any water from the bags.

After that all fishes is transferred to the low pH receiving aquaria – start aeration of the low pH aquaria. This will slowly rise the pH and the next day you can transfer your fish to your QT or to your aquaria.

During the whole process – work slow – do not stress the fish – do not feed before you have transferred your fish into QT or DT.


Another method is to use an ammonia blocking agent in the bag – but as I understand – you can´t use that if there is copper in the transport water or in your receiving tank.

I always transfer my fish to my refugium (very much of pods there) and let them stay there for a week or two before transfer to my DT. Observe – I do it with fish that I know its healthy and in a country that are rather free of different illness. I do not say that QT is wrong – at least if you do not use prophylactic methods.

What I´ll try to say is that maybe the method to use prophylactic´s has been so widely used in the US that resistant population of some microorganisms has evolved. There is also other problems with using drugs to treat fishes (with drugs I also count in cupper). To be effective – drugs must be toxic in one or another way and it is only the dosage that judge if it will kill or treat our fishes. If it is a toxic substance – it must be (even if it is in low concentrations) made harmless (detoxification) by the fish and be transported out from the body or be bound in the fat of the fish (read chlorine organics).

The detoxification process happens mostly in the liver in an enzyme system (enzyme cascade) called the MFO system and especially the P-450 enzyme system. In a cascade of processes – the toxic substance gradually will be change to the end product - a more tolerated substance or an ineffective. But this system is a cascade of enzymatic processes – every enzyme creating metabolites that will be processed in the next step. This temporary metabolite can be more toxic than the original substance – therefore is important that the process can work without any breaks. A famous compound - just stopping this process in a certain step with a toxic substance – is antabuse (disulfiram). It stops the breakdown of alcohol in a certain step – leaving a metabolite that you do not feel very well with. And there are people that does not have a good enzymatic breakdown process for alcohol in their MFO – these get drunk fast and for a long period.

And – more to come – the MFO system is an evolutionary system – the enzymes in the P-450 system can be changed to co-enzymes in order to take care of substances it has never seen before. These substances are named inducer and there is a lot of them. The problem with them is that the co-enzyme produced of them can be fatal for the normal treatment of endogenous substances – they can attack wrong part of the molecule – hence create dangerous metabolites of endogenous substances. A lot of chlorine organics is well known to act in this way.

Among drugs acting on the P-450 enzyme system (in one or another way) are (no surprise for me) Chloroquine, metronidazole, erythromycin and fluconazole – all in normal us in the US but forbidden for use without a description of a veterinary in Sweden. I also think that all of these can create resistant population of different microorganisms – however not sure on all four.

With the chlorine organics – there is another troubling fact. These substances are soluble in fat – Fat is the primary energy source for fishes and store fat as reserves. This means that they also store things that are solved in fat. Total chlorine content in fishes can be high. What do you use the energy reserves to? Exact – when you have use for energy and do not get it through your food. Transport, stress and other factors will use energy – energy comes from the fat – fat disappear, and the solved chlorine organics comes out in the blood system again. There is some evidences that a M-74 (a known illness among Baltic salmons) is caused by this release of organic chlorines in the bloodstream. High levels of antioxidants seems to counteract this.

About the use of copper at low concentrations – there is a lot of literature – Just Google “sublethal exposure of copper fish

This post become long and complicated - therefore some words about another circumstance that make the use of pre-treatment for salt water species a little bit more complicated :) . A saltwater fish drinks a lot but pee very little – if all. The normal transfer path for substances that has been processed by the detoxification system (they have become more soluble in water) are through the kidneys and the pee. The salt water species do not pee as much as freshwater species – this means that the residues of different compounds will be in the fish body much longer and the rate of detoxification can be altered.

I will not more than mention the problems with introducing a already weakened fish to a new bacterial and parasite environment. The sickness can be induced from your home aquaria too!

Back to the original question

Facts show –

At the collector station/export facilities there can be use of both copper, chloroquine and other drugs.

At the wholesaler – the same situation

At the LFS – the same situation

At home - ?


This means that the poor fish in 30 to 60 days can been treated with low level of copper the whole time and been out for 3 treatments of the same drug (and you do not know the concentrations) – this before it arrives to your home – and you are starting a new cycle of treatment without any signs of diseases?

If there are signs of disease – treat – no doubt – but do not fix anything that´s not broken.

Somewhere this spiral must end - best has been if it end already at the wholesalers.

Sincerely Lasse
Huh? So what do you recommend?
 
Do not use any medication at all if there is now sign of diseases. Do not dose any thing just in case! If there is sign - use the proper medication. If you QT - let the fish go there and make a non stressfull environment for them - do not dose medications just in case. Do not fix anything that´s not broken!

That´s my advices - and the reasons for them - you can read in the write up that you cited.

Sincerely Lasse
 

IF YOU HAD TO TAKE A REEFING EXAM, WOULD YOU PASS?

  • Yes!

    Votes: 32 45.7%
  • Not yet, but I have one that I want to buy in mind!

    Votes: 9 12.9%
  • No.

    Votes: 26 37.1%
  • Other (please explain).

    Votes: 3 4.3%
Back
Top