I would do your waterchange from the larger tank, dump what you are going to remove from the pico, add what you remove from the other tank.
Good idea. It's how I cycled the tank to start
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I would do your waterchange from the larger tank, dump what you are going to remove from the pico, add what you remove from the other tank.

How long have you running chemi pure? Remember activated carbon also takes out trace elements

