Yes, I just started up my new 120gallon with bp from day one. I have tried read about biopellets as much as I possibly can and I am still being very careful. I choose the Ecobak Plus pellets which claim to have a new blend of polymers that also target phosphates
I'll give you a few points I've learned that can help in getting started. I invite anyone else to chime in if I missed something.
1) Get a recirculating reactor, there aren't many in the market. I bought mine from Aqualund, he can custom make you one a decent price. Reefdyanmics had the best recir reactor on the market but they shutdown the business right when I was about to order mine.
2) Get a great skimmer, I went 1+ which means to get the skimmer above the one rated for your system water volume
3) Point the water coming out of the reactor as close to the skimmer intake as possible.
4) Start SLOW if your system has already been running but if you start the bp from day one you can get away with the full recommended amount for your system. Start with a quarter of the recommended amount and every two weeks add another quarter of bp's until you get to the desired amount.
So far I've been running the tank for 3 months and the skimmer has been producing some nasty gunk. The video link below helped me understand bp's and the recirculating reactor a lot better. Hope this helps
Part 1
Part 2
Now reading my response I should have maybe just said, Yes to your question. lol sorry