But is this repeatable long term for more hobbyists? Not likely.
I don't know, but we do know that having fish get sick and die after or more likely during quarantine is very repeatable. Just look at the disease forum. I can do it and I am not that smart.
I also think I do much less to my tank than anyone here. I rarely change water, don't test, rarely dose and never have to observe fish before I add them as I consider parasites, any parasite a good thing and not a bad one. Parasites are alive and well in my tank probably practicing line dancing right now as they live out their life and try to infect my fish which in turn keeps the fish healthy. Right now my old copperband has some spots on her tail. They are old dead parasites and by seeing those, I know the fish is immune. I realize my ways are totally opposite from what all of us have learned but it is odd that my way "never" has problems and I have been doing this a very long time.
The only thing I do different is keep a natural tank. By that I mean I don't have to vacuum detritus (you can't find any in there anyway because of the RUGF) I would never quarantine and I feed almost every day with something that has live bacteria in it like clams or worms. The vast majority of what I feed is commercial LRS food.
If I were to start up a tank today I think I would add the water and rocks. Try to get some real water or I would use mud from my garden. After the thing settled down I would add some fish. Some would get sick. That is fine and to me, means all is well because they can't get immune unless they are exposed to something to become immune to.
The way many people go is to carefully find a fish, quarantine it for 72 days (in which time most fish would exhibit some sort of disease due to the enormous stress placed on the creature) Then if it does get sick, dip it, then medicate it and hope it survives.
Why don't I have to do that?
It's because fish can and need to live with disease causing bacteria and parasites to stay healthy. It is a huge part of their being and the largest energy user in their body. Just constantly making slime with anti bodies in it uses more energy than growth and reproduction. But you can't short circuit that system and expect a fish to be normal.
Why do we get flu, measles and pneumonia shots? It's because we are not exposed to those things constantly like we used to be so we lose resistance. If we lived in a Jungle in Viet Nam all our life and we were otherwise healthy, we would not get Malaria even though we would be exposed every day.
In the sea fish are exposed to and eat parasites and disease pathogens with every meal. Did you ever see a sick fish in the sea? I have not unless it was wounded and I have spent all most 300 hours underwater.
Until we learn how to naturally live with parasites and other diseases rather than fight them, we will unfortunately always have disease threads and IMO there is no need for them.