Bryopsis Cure: My Battle With Bryopsis Using Fluconazole
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NCreefguy
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Vibrant seems to be doing that for a lot of people's tanks. After my Fluconazole treatment I ran two days of chemiclean to get rid of my cyano. It hasn't come back yet.
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NCreefguy
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I would wait just to see if your bryopsis dies without adding more. Some have still had success while running their skimmer.I'm not saying it would hurt to add more but some people's algae dies using less flucon.
prsnlty
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+1 Vibrant is the cause of cyano. Had this happen to me as well. Looks like the algae smothered the frags. When fluconazole kills it off and after you do chemiclean they may come back.
Correction (dumb phone)... +1 Vibrant causes the cyanobacteria outbreaks on a good majority of the systems being treated with it.
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NCreefguy
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I didn't want to use it at the same time because I was testing Fluconazole alone to see if anything had any adverse reactions. I also figured one treatment at a time was enough.There haven't been enough tests yet to say if the two are safe enough to run at the same time. Twilliard is still in the process of growing some algae to run his tests.
cnseekatz
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I didn't turn off my skimmer, or my UV sterilizer, and my bryo was totally gone in 10 days. I did turn off my media (ChemiPure) reactor for a few days though.
KenO
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My wife understands the scientific stuff and pointed me to a website that had this information:
Figure 57–1 Sites of action of antifungal drugs. Amphotericin B and other polyenes (e.g., nystatin) bind to ergosterol in fungal cell membranes and increase membrane permeability. The imidazoles and triazoles (itraconazole, et al.) inhibit 14-α-sterol demethylase, prevent ergosterol synthesis, and lead to the accumulation of 14-α-methylsterols. The allylamines (e.g., naftifine and terbinafine) inhibit squalene epoxidase and prevent ergosterol synthesis. The echinocandins, such as caspofungin, inhibit the formation of glucans in the fungal cell wall.
I was explaining to her that some folks have good and fast results others do not. Her thoughts were that if the Fluconazole is either absorbed by the Bryopsis or GHA or something else in the tank, and not enough is available that could lead to slower or less than optimum results. Depending on how severe the outbreak is, the Flucon could be getting used up before it eliminates the algae. For people, it sounds as if there are cases where they load up and do a high dose for a few days and then cut back for the rest of the treatment period. So some people may need additional doses to fully eliminate it.
Figure 57–1 Sites of action of antifungal drugs. Amphotericin B and other polyenes (e.g., nystatin) bind to ergosterol in fungal cell membranes and increase membrane permeability. The imidazoles and triazoles (itraconazole, et al.) inhibit 14-α-sterol demethylase, prevent ergosterol synthesis, and lead to the accumulation of 14-α-methylsterols. The allylamines (e.g., naftifine and terbinafine) inhibit squalene epoxidase and prevent ergosterol synthesis. The echinocandins, such as caspofungin, inhibit the formation of glucans in the fungal cell wall.
I was explaining to her that some folks have good and fast results others do not. Her thoughts were that if the Fluconazole is either absorbed by the Bryopsis or GHA or something else in the tank, and not enough is available that could lead to slower or less than optimum results. Depending on how severe the outbreak is, the Flucon could be getting used up before it eliminates the algae. For people, it sounds as if there are cases where they load up and do a high dose for a few days and then cut back for the rest of the treatment period. So some people may need additional doses to fully eliminate it.
d2mini
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This is the mess in my fuge. Red macros and some cheato, with a whole lot of HA and who knows what mixed in.
I'm going to cut back to just a few hours a night rather than the current 8 hour schedule.
Skimmer cup, ozone and carbon is off now too.
I'm going to cut back to just a few hours a night rather than the current 8 hour schedule.
Skimmer cup, ozone and carbon is off now too.
mta_morrow
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Day 5 vs gha and areas in the highest light are turning white. Darker and shaded areas I see nothing yet.
Im starting to doubt how effective this stuff is against Derbasia.
I dosed Fluco early Saturday afternoon after a water change and while I do realize its only been 48 hours, Im noticing now that Im home from work that in some areas the derbasia has grown or become more full. I also feel like in seeing some pictures of other folks who are having a hard time that some of their algae looks more similar to derbasia than to bryopsis.
Im going back and forth on whether I want to start a 2nd dose, especially so early into the first treatment. I took away the filter socks, have my skimmer turned off and also the GFO/Carbon reactor. Im definitely seeing the effects of that as I had to clean my glass today when I usually dont have to do that til Wednesday at the earliest.
Ive read this entire thread and I do know that people have said it takes longer for this to remove derbasia, but the fact the mine has shown signs of health and possibly growth after 48 hours is not encouraging. I feel like all Im doing right now is helping to feed the stuff with all my filtration equipment turned off
That being said, if Im wrong, Ill be the first one doing backflips
I dosed Fluco early Saturday afternoon after a water change and while I do realize its only been 48 hours, Im noticing now that Im home from work that in some areas the derbasia has grown or become more full. I also feel like in seeing some pictures of other folks who are having a hard time that some of their algae looks more similar to derbasia than to bryopsis.
Im going back and forth on whether I want to start a 2nd dose, especially so early into the first treatment. I took away the filter socks, have my skimmer turned off and also the GFO/Carbon reactor. Im definitely seeing the effects of that as I had to clean my glass today when I usually dont have to do that til Wednesday at the earliest.
Ive read this entire thread and I do know that people have said it takes longer for this to remove derbasia, but the fact the mine has shown signs of health and possibly growth after 48 hours is not encouraging. I feel like all Im doing right now is helping to feed the stuff with all my filtration equipment turned off
That being said, if Im wrong, Ill be the first one doing backflips
redfishbluefish
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I do apologize as we approach 1400 posts in this thread, and I haven't read them all, but I don't recall a single post stating that fluconazole does anything for derbasia. It's for bryopsis....with some now starting to report some impact on gha....but that's yet to be seen with clear proof. Where did you see this impacting derbasia?
EDIT TO ADD: Derbasia could be GHA. Again, yet to be proven.
Derbasia is not GHA, its turf algae. Its more similar to bryopsis than it is to GHA. Like Bryopsis, its hard to manually remove, it can survive in low nutrient systems, and also in areas with little to no light.
If youre looking for a post in this thread where it says this stuff can kill Derbesia you can look no further than Page 1, Post 1. Theres also several other posts and pictures where its mentioned throughout the thread. Some pictures looked like derbesia some didnt.
Q: What other nuisance algae's will be killed by Fluconazole?
A: Fluconazole kills the green algae Derbesia also known as GHA. It seems that GHA takes longer to kill than the bryopsis but it still dies. Bubble algae is unknown due to most reefers treating their tanks have been using Vibrant. Vibrant kills bubble algae very well.
Im not trying to sound snarky or anything, its pretty obvious from the results on this thread and others that Fluco kills Bryopsis, Im just pointing out that we may need to pump the brakes on lumping Derbesia or turf algae into the equation as well. Also, i think constantly referring to Derbasia as GHA is a mistake, even if you want to classify Derbasia as a form of GHA, it is SIGNIFICANTLY more difficult to remove than your regular run of the mill GHA. This can lead to some of the confusion when people are saying it works in one case and not the other.
Just one mans opinion
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ENARP
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Please let me know if I am correct on my calculation of the proper dosage and procedures. I ordered 10 - 200mg tablets of Fluconazole. I have a 45 gallon tank, so by my calculations at 20mg / gal, a 45 gallon tank needs a 900mg single dose. At 200mg per tablet, I will need to dose 4 1/2 tablets. Before dosing I will remove all carbon and turn off skimmer. Then the waiting game begins with no water changes for 12 days.
jason_mazzy
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Any red algaes react?
