Ok. So, having a powerhead in the tank will help your entire tank be healthy for the long term. Having proper flow through the tank is necessary for the fish's health and if you have or get corals for their health too. Having one pointed toward the surface of the water will help oxygenate the water much better than your HOB filter as well.
For now, you can perform a Freshwater dip on the female clown. Your checking for flukes with this and is probably the best next step to figuring out what's going on with her. Here's how:
Freshwater Dip: Provides temporary relief for Brooklynella, Flukes & "Black Ich", Marine Velvet disease (Amyloodinium); possibly even Ich & Uronema marinum (both unproven). Can be used to confirm the presence of Flukes.
How To Treat - Fill a bucket with RODI water, and use a heater to match the temperature to the water the fish is coming from. Aerate the water heavily for at least 30 minutes prior to doing the dip, then discontinue aeration while performing the dip. Fish aren’t overly pH sensitive for short durations like this, but you can squirt a little tank water into the dip just before the fish goes in to help bring it up.
Place the fish in the freshwater (FW) dip and observe closely. It is not unusual for them to freak out a little at first. Also, tangs are notorious for “playing dead” during a FW dip. The important thing is to watch their gills; they should be breathing heavily at all times during the dip. If breathing slows, it’s time to exit the dip. Dip the fish for no longer than 5 minutes. Multiple dips may be done, but it’s important to give your fish a day to recuperate in-between dips.
For flukes, use a dark (preferably black) bucket so you can see if tiny white worms fall out of the fish (especially out of the gills) at around the 3-4 minute mark. The worms will settle to the bottom, so you can use a flashlight to look for them there as well.
Pros - Provides temporary relief for a wide range of diseases in a chemical free environment. Can “buy you more time” until a proper treatment can be done.
Cons/Side Effects - Not a permanent “fix” for any disease, as FW dips are not potent enough to eradicate
all of the parasites/worms afflicting the fish. Some fish can have an adverse reaction to a FW dip by appearing unable to maintain their equilibrium once returned to the aquarium. If this happens, hold the fish upright (using latex, nitrile or rubber gloves), and gently glide him through the water (to get saltwater flowing through the gills again). It is also a good idea to place the fish in an acclimation box until he appears “normal”.
Here is what to look for:
